Large U-tail fiber chromatography
The length of the poly(A) tail has direct impact on the stability and translation efficiency of the mRNA molecule and is therefor. The method relies on the digestion of an mRNA molecule with RNase T1 to release the poly(A) tail and an optimized ion-pairing mobile phase system for separation of poly(A) tail length variants. Overcome chromatography challenges with fiber adsorbents Shop in your local currency and language Choose another country or region to see specific content for your location and shop online.
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