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Celebrating International Women and Girls in Science Day, this blog shares insights from PLOS One Section Editors and Professor Claire Brockett on barriers women face in science, the
Microbiological cross-contamination has been a contributing factor to several well-documented outbreaks of foodborne illness.
In this article, we outline the application of LOPA to product and facility cross contamination. A function of the LOPA for cross contamination is to
Visual inspection should include all product contact surfaces where contamination may be held, including those that require dismantling of equipment to gain access for inspection and/or by use of
In this section, four tactics will be discussed: environmental swabbing, positivity rate monitoring, use of process controls, and monitoring complaints (Table 1).
This phase focuses on the systematic identification of all potential contamination sources, vectors, and routes that could compromise product quality in the manufacturing environment.
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Learn how to detect possible risks, how to avoid cross contamination, how to determine exposure limits. Cross Contamination is one of the highest risks for patients using pharmaceutical products.
Layers of protection analysis (LOPA) is a risk tool that focuses on the strength of controls that are currently in place and enables a cross-functional
Conclusion Contamination, cross-contamination, and mix-ups are serious threats in pharmaceutical manufacturing that can compromise product
Identify clearly where specific separation or dedicated parts, equipment or area is required based on an unreasonable risk of failure or difficulty to control otherwise.
The root cause for contamination and cross-contamination can range from technical issues to quality system deficiencies, and some common sources of contamination are identified in Figure 1 below.
Learn how to assess and reduce cross-contamination risks in GMP to ensure product safety and quality compliance.
A pediatric infectious disease specialist explains the concept of cross-contamination and shares tips to reduce the risk of it happening in your kitchen.
Managing the Unintended Transfer of Contaminants A cross-contamination risk assessment is a systematic evaluation of potential sources
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Companies rely on the Quality Risk Management (QRM) program that is integrated into their PQS to conduct risk assessment and subsequent implementation of contamination control strategies (CCS)
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Usually every 1-2 years, the test is performed using various reference sources of the radionuclide source of interest (e.g. planchets or planar sources) with a traceable surface emission rates of different
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Discover how to create a cross-contamination risk assessment as a part of a Contamination Control Strategy to ensure compliance and safeguard
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Learn how to detect and prevent cell culture contamination. Practical tips to avoid bacteria, fungi, mycoplasma, viruses, and cross-contamination.
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